{"id":892,"date":"2023-12-18T23:07:00","date_gmt":"2023-12-18T14:07:00","guid":{"rendered":"https:\/\/healthstar.kr\/?p=892"},"modified":"2024-01-25T01:12:34","modified_gmt":"2024-01-24T16:12:34","slug":"%ea%b0%b1%eb%85%84%ea%b8%b0-%ec%9c%a0%ec%82%b0%ea%b7%a0-yt1-%ed%9a%a8%ea%b3%bc-%ec%8b%a4%ed%97%98-%ea%b7%bc%ea%b1%b0-%ed%99%95%ec%9d%b8%ed%95%b4-%eb%b3%b4%ec%84%b8%ec%9a%94","status":"publish","type":"post","link":"https:\/\/healthstar.kr\/%ea%b0%b1%eb%85%84%ea%b8%b0-%ec%9c%a0%ec%82%b0%ea%b7%a0-yt1-%ed%9a%a8%ea%b3%bc-%ec%8b%a4%ed%97%98-%ea%b7%bc%ea%b1%b0-%ed%99%95%ec%9d%b8%ed%95%b4-%eb%b3%b4%ec%84%b8%ec%9a%94\/","title":{"rendered":"\uac31\ub144\uae30 \uc720\uc0b0\uade0 YT1, \ud6a8\uacfc \uc2e4\ud5d8 \uadfc\uac70 \ud655\uc778\ud574 \ubcf4\uc138\uc694!"},"content":{"rendered":"\n

\uc624\ub298\uc740 \ub9ce\uc740 \ubd84\ub4e4\uc774 \uad81\uae08\ud574 \ud558\ub294 \ud504\ub85c\ubc14\uc774\uc624\ud2f1\uc2a4 L. acidophilus YT1(\ub77d\ud1a0\ubc14\uc2e4\ub7ec\uc2a4 \uc544\uc2dc\ub3c4\ud544\ub8e8\uc2a4 YT1)\uc758 \uac31\ub144\uae30 \uc99d\uc0c1 \uc644\ud654 \ud6a8\uacfc\uc5d0 \ub300\ud574 \uc804\uc784\uc0c1 \uc2e4\ud5d8 \uc5f0\uad6c \uc2e4\ud5d8 \uc790\ub8cc\ub97c \uc870\uae08\uc774\ub77c\ub3c4 \uc774\ud574\ub97c \ub3d5\uae30 \uc704\ud574 \uc815\ubcf4\ub97c \uc900\ube44\ud588\uc2b5\ub2c8\ub2e4.

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\"\uac31\ub144\uae30<\/figure>\n\n\n\n

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\uac31\ub144\uae30 \ub3d9\ubb3c\ubaa8\ub378(Lactobacillus acidophilus YT1\uc758 \uac10\uc1e0 \ud6a8\uacfc \ub09c\uc18c\uc808\uc81c\uc220\uc744 \ubc1b\uc740 \uc950\uc758 \uac31\ub144\uae30 \uc99d\uc0c1)\uc5d0\uc11c Lactobacillus acidophilus YT1\uc758 \uac31\ub144\uae30 \uc99d\uc0c1 \uc644\ud654 \ud6a8\uacfc<\/strong><\/p>\n\n\n\n

\ud604\ub300 \uc758\ud559 \uae30\uc220\uacfc \uacbd\uc81c \uc218\uc900\uc758 \ud5a5\uc0c1\uc73c\ub85c \uc778\ud574 \uc6b0\ub9ac \uc0ac\ud68c\ub294 \uc810\uc810 \uace0\ub839\ud654\ub418\uace0 \uc788\uc2b5\ub2c8\ub2e4. \ud1b5\uacc4\uccad\uc5d0 \ub530\ub974\uba74 1970\ub144\uc5d0\ub294 \uc5ec\uc131\uc758 \ud3c9\uade0 \uae30\ub300\uc218\uba85\uc774 65.6\uc138\uc600\uc9c0\ub9cc 2015\ub144\uc5d0\ub294 \ud06c\uac8c \uc99d\uac00\ud558\uc5ec 85.2\uc138\uae4c\uc9c0 \uc62c\ub790\uc2b5\ub2c8\ub2e4. \uc774\uc5d0 \ub530\ub77c \uc5ec\uc131\ub4e4\uc740 \ud3d0\uacbd \ud6c4\uc758 \uc218\uba85\ub3c4 \uc99d\uac00\ud558\uba70, \uc774\ub85c \uc778\ud574 \ud3d0\uacbd \ud6c4 \uac74\uac15\uad00\ub9ac\uc5d0 \ub300\ud55c \uad00\uc2ec\ub3c4 \uacc4\uc18d\ud574\uc11c \uc99d\uac00\ud558\uace0 \uc788\uc2b5\ub2c8\ub2e4.

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\ud3d0\uacbd \ud6c4 \uc5ec\uc131\uc740 \ub09c\uc18c \uae30\ub2a5 \uc18c\uc2e4\ub85c \uc778\ud574 \uc790\uc5f0\uc2a4\ub7fd\uac8c \uac31\ub144\uae30 \uc99d\uc0c1\uc744 \uacbd\ud5d8\ud558\uac8c \ub429\ub2c8\ub2e4. \uc774\ub7ec\ud55c \ubcc0\ud654\ub294 \uc2e0\uccb4\uc801\uc778 \ubcc0\ud654\ubfd0\ub9cc \uc544\ub2c8\ub77c \uac10\uc815\uc801\uc778 \ubcc0\ud654\ub3c4 \ub3d9\ubc18\ub429\ub2c8\ub2e4. \uc8fc\uc694\ud55c \uac31\ub144\uae30 \uc99d\uc0c1\uc73c\ub85c\ub294 \ud64d\uc870, \uc57c\uac04 \ub540, \uae30\uc5b5\ub825 \uac10\ud1f4, \uc6b0\uc6b8\uc99d, \uc218\uba74 \uc7a5\uc560, \ube44\ub9cc, \ud1b5\uc99d \uacfc\ubbfc \ub4f1\uc774 \uc788\uc73c\uba70, \uace8\ub2e4\uacf5\uc99d, \uac04 \uc9c8\ud658, \uc2ec\ud608\uad00 \uc9c8\ud658 \ub4f1 \ub2e4\uc591\ud55c \uc9c8\ubcd1\uc758 \ubc1c\ubcd1 \uc704\ud5d8\ub3c4 \uc99d\uac00\ud569\ub2c8\ub2e4.

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\uae30\uc874\uc758 \uac31\ub144\uae30 \uc99d\uc0c1 \uc644\ud654\ub97c \uc704\ud574 \ud638\ub974\ubaac \ub300\uccb4 \uc694\ubc95(HRT)\uc774 \ub9ce\uc774 \uc0ac\uc6a9\ub418\uc5c8\uc9c0\ub9cc, \uc7a5\uae30\uac04 \uc0ac\uc6a9 \uc2dc \uc2ec\ud608\uad00 \uc9c8\ud658, \uc720\ubc29\uc554, \uad00\uc0c1\ub3d9\ub9e5\uc131 \uc2ec\uc7a5\ubcd1, \ub1cc\uc878\uc911, \ub09c\uc18c\uc554 \ub4f1\uc758 \uc9c8\ubcd1 \ubc1c\uc0dd \uc704\ud5d8\uc774 \uc99d\uac00\ud558\ubbc0\ub85c \ubd80\uc791\uc6a9\uc774 \uc801\uc740 \uc0c8\ub85c\uc6b4 \uc811\uadfc\ubc95\uc758 \uac1c\ubc1c\uc774 \ud544\uc694\ud558\uc600\uc2b5\ub2c8\ub2e4. \uc774\uc5d0 \uc2dd\ubb3c\uc131 \uc5d0\uc2a4\ud2b8\ub85c\uac90\uc778 \uc11d\ub958 \ucd94\ucd9c\ubb3c\uc774\ub098 \ubc31\ud558\uc218\uc624 \ub4f1\uc774 \uac31\ub144\uae30 \uc99d\uc0c1 \uc644\ud654\uc5d0 \ub3c4\uc6c0\uc774 \ub420 \uc218 \uc788\ub2e4\ub294 \uc5f0\uad6c \uacb0\uacfc\uac00 \ubcf4\uace0\ub418\uc5c8\uc2b5\ub2c8\ub2e4.

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\ub610\ud55c \ud504\ub85c\ubc14\uc774\uc624\ud2f1\uc2a4\ub294 \uc138\uacc4\ubcf4\uac74\uae30\uad6c\uc5d0\uc11c “\uc801\ub2f9\ub7c9 \uc12d\ucde8 \uc2dc \uc219\uc8fc\uc5d0\uac8c \uac74\uac15\uc0c1 \uc720\uc775\ud55c \ud6a8\uacfc\ub97c \uc8fc\ub294 \uc0b4\uc544\uc788\ub294 \ubbf8\uc0dd\ubb3c”\ub85c \uc815\uc758\ub418\uba70, \uc18c\ud654 \uae30\ub2a5 \uac1c\uc120, \ud53c\ubd80 \uac74\uac15 \uc99d\uc9c4, \uba74\uc5ed\ub825 \uac15\ud654, \ucf5c\ub808\uc2a4\ud14c\ub864 \uc800\ud558 \ub4f1 \ub2e4\uc591\ud55c \uc601\uc5ed\uc5d0\uc11c \uac74\uac15 \uac1c\uc120 \ud6a8\ub2a5\uc774 \ubcf4\uace0\ub418\uace0 \uc788\uc2b5\ub2c8\ub2e4. \ud2b9\ud788 \uc720\uc0b0\uade0\uc778 Lactobacillus acidophilus\ub294 \uc720\uc81c\ud488 \uc81c\uc870\uc5d0 \uc0ac\uc6a9\ub418\ub294 \uc720\uc0b0\uade0 \uc911 \ud558\ub098\ub85c \ub110\ub9ac \uc54c\ub824\uc838 \uc788\uc73c\uba70, \uc544\ud1a0\ud53c\ud53c\ubd80\uc5fc, \ucc9c\uc2dd\uacfc \uac19\uc740 \uc54c\ub808\ub974\uae30 \uc9c8\ud658 \uac1c\uc120\uc5d0\ub3c4 \ub3c4\uc6c0\uc744 \uc900\ub2e4\uace0 \uc54c\ub824\uc838 \uc788\uc2b5\ub2c8\ub2e4.

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\ucd5c\uadfc\uc758 \uc5f0\uad6c\uc5d0\uc11c\ub294 \uac31\ub144\uae30 \ub3d9\ubb3c\ubaa8\ub378\uc5d0\uc11c L. acidophilus\uc758 \ud22c\uc5ec\uac00 \uace8\ubc00\ub3c4 \uac1c\uc120, \ud1b5\uc99d \uacfc\ubbfc, \uccb4\uc9c0\ubc29 \uc99d\uac00, \uc6b0\uc6b8\uc99d \ub4f1 \ub2e4\uc591\ud55c \uac31\ub144\uae30 \uc99d\uc0c1 \uc644\ud654\uc5d0 \ud6a8\uacfc\uac00 \uc788\ub2e4\ub294 \uc0ac\uc2e4\uc774 \ubc1d\ud600\uc84c\uc2b5\ub2c8\ub2e4.

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\ub530\ub77c\uc11c \ubcf8 \uc5f0\uad6c\uc5d0\uc11c\ub294 \ub09c\uc18c\uc808\uc81c \ub3d9\ubb3c\ubaa8\ub378\uc5d0\uc11c \uc2e0\uaddc \ud504\ub85c\ubc14\uc774\uc624\ud2f1\uc2a4 \ud6c4\ubcf4 \uade0\uc8fc\uc778 L. acidophilus YT1\uc758 \ud22c\uc5ec\uac00 \uac31\ub144\uae30 \uc99d\uc0c1 \uac1c\uc120\uc5d0 \uc5b4\ub5a0\ud55c \ud6a8\uacfc\uac00 \uc788\ub294\uc9c0 \ud655\uc778\ud558\uace0\uc790 \ud569\ub2c8\ub2e4.



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\uac31\ub144\uae30 \ubaa8\ub378\uc5d0\uc11c\uc758 \ud1b5\uc99d \ubbfc\uac10\ub3c4 \ubcc0\ud654 \uce21\uc815<\/h2>\n\n\n\n

\ubcf8 \uc2e4\ud5d8\uc5d0\uc11c\ub294 \uac31\ub144\uae30 \ub3d9\ubb3c \ubaa8\ub378\uc5d0 \ub300\ud558\uc5ec 12\uc8fc \ub3d9\uc548 \ub2e4\uc591\ud55c \ucc98\ub9ac\ub97c \uc2dc\ud589\ud55c \ud6c4 \ud1b5\uc99d \ubbfc\uac10\ub3c4\ub97c \uce21\uc815\ud558\uc600\uc2b5\ub2c8\ub2e4. \uacb0\uacfc\uc801\uc73c\ub85c, Sham \uadf8\ub8f9\uc5d0 \ube44\ud574 OVX \uadf8\ub8f9\uc5d0\uc11c\ub294 \ud1b5\uacc4\uc801\uc73c\ub85c \uc720\uc758\ud55c \ud1b5\uc99d \ubbfc\uac10\ub3c4\uc758 \uc99d\uac00\uac00 \uad00\ucc30\ub418\uc5c8\uc2b5\ub2c8\ub2e4(P<0.01). \uadf8\ub7ec\ub098 estradiol \ud22c\uc5ec \uadf8\ub8f9\uacfc L. acidophilus YT1 \ud22c\uc5ec \uadf8\ub8f9\uc5d0\uc11c\ub294 OVX \uadf8\ub8f9\uc5d0 \ube44\ud574 \ud1b5\uc99d \ubbfc\uac10\ub3c4\uc758 \uac10\uc18c\uac00 \uc720\uc758\uc801\uc73c\ub85c \ub098\ud0c0\ub0ac\uc2b5\ub2c8\ub2e4(P<0.001). \uc774\ub294 L. acidophilus YT1\uc758 \ud22c\uc5ec\uac00 \uac31\ub144\uae30 \uc99d\uc0c1 \uc911 \ud1b5\uc99d \ubbfc\uac10\ub3c4\ub97c \uac10\uc18c\uc2dc\ud0a4\ub294\ub370 \ud6a8\uacfc\uc801\uc784\uc744 \uc2dc\uc0ac\ud569\ub2c8\ub2e4.

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\uac31\ub144\uae30 \uc5ec\uc131\ub4e4\uc744 \ub300\uc0c1\uc73c\ub85c \ud55c \ud1b5\uc99d \ubbfc\uac10\ub3c4 \uce21\uc815 \uc5f0\uad6c\uc5d0\uc11c\ub294 \ud1b5\uc99d \ubbfc\uac10\ub3c4\uac00 \ub192\uc740 \uc5ec\uc131\ub4e4\uc774 \uc5d0\uc2a4\ud2b8\ub85c\uac90 \uc218\uce58\uac00 \ub0ae\uc740 \uac83\uc73c\ub85c \ub098\ud0c0\ub0ac\uc2b5\ub2c8\ub2e4. \uc774\ub294 \uac31\ub144\uae30 \uc5ec\uc131\ub4e4\uc774 \ud1b5\uc99d\uc5d0 \ubbfc\uac10\ud558\ub2e4\ub294 \uc0ac\uc2e4\uc744 \ubcf4\uc5ec\uc90d\ub2c8\ub2e4(2). \uc774\uc640 \ub354\ubd88\uc5b4 \uc774\uc804\uc758 \uac31\ub144\uae30 \ub3d9\ubb3c \ubaa8\ub378\uc744 \uc0ac\uc6a9\ud55c \uc5f0\uad6c\uc5d0\uc11c\ub3c4 von-Frey \ud544\ub77c\uba58\ud2b8 \uc2e4\ud5d8\uc744 \ud1b5\ud55c \ud1b5\uc99d \ubc18\uc751 \uc5ed\uce58\uac12\uc758 \uac10\uc18c\uac00 \uad00\ucc30\ub418\uc5c8\uc73c\uba70, \uc774\ub294 \uac31\ub144\uae30\uc5d0 \ud1b5\uc99d \ubbfc\uac10\ub3c4\uac00 \uc99d\uac00\ud558\ub294 \uac83\uc744 \uc758\ubbf8\ud569\ub2c8\ub2e4(19). \ub610\ud55c \uac31\ub144\uae30 \ub3d9\ubb3c \ubaa8\ub378\uc5d0\uc11c\ub294 \uc5f4\uc801 \ud1b5\uac01\uacfc\ubbfc(thermal hyperalgesia)\uc744 \uce21\uc815\ud55c \uacb0\uacfc, \ubc18\uc751 \uc2dc\uac04(response latency)\uc774 \uc720\uc758\uc801\uc73c\ub85c \uac10\uc18c\ud558\uba70, 17\u03b2-estradiol \ud22c\uc5ec\ub97c \ud1b5\ud574 \uc774 \ubc18\uc751 \uc2dc\uac04\uc774 \uc720\uc758\uc801\uc73c\ub85c \uc99d\uac00\ud558\ub294 \uac83\uc744 \ud655\uc778\ud560 \uc218 \uc788\uc5c8\uc2b5\ub2c8\ub2e4(20).
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\"\uac31\ub144\uae30<\/figure>\n\n\n\n


\ud504\ub85c\ubc14\uc774\uc624\ud2f1\uc2a4\ub294 \ub2e4\uc591\ud55c \ud1b5\uc99d \ubaa8\ub378\uc5d0\uc11c \ud1b5\uc99d \uc644\ud654\uc5d0 \ub3c4\uc6c0\uc744 \uc900\ub2e4\ub294 \uc5f0\uad6c \uacb0\uacfc\uac00 \uc788\uc2b5\ub2c8\ub2e4. \uc608\ub97c \ub4e4\uc5b4, \ube44\ub9cc\uc73c\ub85c \uc720\ub3c4\ub41c \ud1b5\uc99d \ubaa8\ub378\uc5d0\uc11c Lactobacillus rhamnosus PB01(DSM 14870)\uc758 \ud22c\uc5ec\uac00 \uae30\uacc4\uc801 \uc790\uadf9\uc5d0 \ub300\ud55c \ud1b5\uc99d \ubbfc\uac10\ub3c4\ub97c \uac10\uc18c\uc2dc\ud0a8\ub2e4\uace0 \ubcf4\uace0\ub418\uc5c8\uc73c\uba70(21), L. acidophilus\ub97c \ud568\uc720\ud558\ub294 \uc720\uc0b0\uade0 \ubc30\uc591\uc561(bacterial extracts)\uc774 \ud654\ud559\uc694\ubc95 \uc720\ub3c4 \uc2e0\uacbd\ubcd1\uc99d\uc131 \ud1b5\uc99d \ub3d9\ubb3c\ubaa8\ub378\uc5d0\uc11c \ud1b5\uc99d \ubbfc\uac10\ub3c4\ub97c \uc644\ud654\uc2dc\ud0a8\ub2e4\ub294 \ubcf4\uace0\uac00 \uc788\uc2b5\ub2c8\ub2e4(22). \uc774\ub7ec\ud55c \uc5f0\uad6c \uacb0\uacfc\ub97c \uace0\ub824\ud558\uba74, \ubcf8 \uc5f0\uad6c\ub97c \ud1b5\ud574 \ud504\ub85c\ubc14\uc774\uc624\ud2f1\uc2a4\uac00 \ube44\ub9cc \uc720\ub3c4 \ud1b5\uc99d\uc774\ub098 \ud654\ud559\uc694\ubc95 \uc720\ub3c4 \uc2e0\uacbd\ubcd1\uc99d\uc131 \ud1b5\uc99d \ubfd0\ub9cc \uc544\ub2c8\ub77c \uac31\ub144\uae30 \ub3d9\ubb3c \ubaa8\ub378\uc5d0\uc11c\ub3c4 \ud1b5\uc99d \ubbfc\uac10\ub3c4\ub97c \uac10\uc18c\uc2dc\ud0ac \uc218 \uc788\uc74c\uc744 \ud655\uc778\ud558\uc600\uc2b5\ub2c8\ub2e4.



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YT1 \ud22c\uc5ec\ub97c \ud1b5\ud55c \uc6b0\uc6b8\uc99d \uad00\ub828 \uc99d\uc0c1 \uc644\ud654
<\/h2>\n\n\n\n

\ubcf8 \uc5f0\uad6c\uc5d0\uc11c\ub294 \uac31\ub144\uae30 \ub3d9\ubb3c \ubaa8\ub378\uc5d0 \ub300\ud558\uc5ec 12\uc8fc \ub3d9\uc548 \ub2e4\uc591\ud55c \ucc98\ub9ac\ub97c \uc2dc\ud589\ud55c \ud6c4 \uc6b0\uc6b8\uc99d \uc720\uc0ac \ud589\ub3d9\uc744 \ud655\uc778\ud558\uc600\uc2b5\ub2c8\ub2e4(Fig. 2). \uacb0\uacfc\uc801\uc73c\ub85c, OVX \uadf8\ub8f9\uc5d0\uc11c\ub294 Sham \uadf8\ub8f9\uc5d0 \ube44\ud574 \uc6b0\uc6b8\uc99d \uc0c1\ud0dc\ub97c \ub098\ud0c0\ub0b4\ub294 \ubd80\ub3d9\uc2dc\uac04\uc774 \uc720\uc758\uc801\uc73c\ub85c \uc99d\uac00\ud558\uc600\uc2b5\ub2c8\ub2e4(P<0.001). \uadf8\ub7ec\ub098 estradiol \ud22c\uc5ec \uadf8\ub8f9\uacfc L. acidophilus YT1 \ud22c\uc5ec \uadf8\ub8f9\uc5d0\uc11c\ub294 OVX \uadf8\ub8f9\uc5d0 \ube44\ud574 \ubd80\ub3d9\uc2dc\uac04\uc774 \uc720\uc758\uc801\uc73c\ub85c \uac10\uc18c\ud558\uc600\uc2b5\ub2c8\ub2e4(P<0.05). \uc774\ub294 L. acidophilus YT1\uc758 \ud22c\uc5ec\uac00 \uac31\ub144\uae30 \ub3d9\ubb3c \ubaa8\ub378\uc5d0\uc11c \uc6b0\uc6b8\uc99d \uc99d\uc0c1\uc744 \uc644\ud654\uc2dc\ud0ac \uc218 \uc788\uc74c\uc744 \uc2dc\uc0ac\ud569\ub2c8\ub2e4.

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\"\"<\/figure>\n\n\n\n


\uc6b0\uc6b8\uc99d\uc740 \uac31\ub144\uae30 \uc5ec\uc131\ub4e4\uc5d0\uac8c \ud754\ud788 \ub098\ud0c0\ub098\ub294 \uc99d\uc0c1 \uc911 \ud558\ub098\ub85c, \uc5d0\uc2a4\ud2b8\ub85c\uac90 \ub18d\ub3c4\uc758 \uac10\uc18c\uc640 \uad00\ub828\ud558\uc5ec \uc2ec\ub9ac\uc801\uc778 \ubcc0\ud654\uac00 \ub098\ud0c0\ub0a9\ub2c8\ub2e4(3). \uc774\uc640 \uad00\ub828\ud558\uc5ec \uac31\ub144\uae30 \ub3d9\ubb3c \ubaa8\ub378\uc5d0\uc11c\ub3c4 \uc6b0\uc6b8\uc99d \uc720\uc0ac \ud589\ub3d9\uc774 \ub098\ud0c0\ub098\uba70, \uc790\ub2f9\uc6a9\uc561 \uc12d\ucde8 \uac80\uc0ac, \uac15\uc81c\uc218\uc601 \uc2e4\ud5d8, \uaf2c\ub9ac \ub9e4\ub2ec\uae30 \ub4f1\uc744 \ud1b5\ud574 \ud655\uc778\ub41c \uc6b0\uc6b8\uc99d \uc720\uc0ac \ud589\ub3d9\uc740 estradiol \ud22c\uc5ec\ub97c \ud1b5\ud574 \uc644\ud654\ub420 \uc218 \uc788\uc2b5\ub2c8\ub2e4(23, 24).

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\ub610\ud55c \uc778\uac04\uc744 \ub300\uc0c1\uc73c\ub85c \ud55c \uc784\uc0c1 \uc5f0\uad6c\uc5d0\uc11c\ub294 \ud2b9\uc815 \ud504\ub85c\ubc14\uc774\uc624\ud2f1\uc2a4 \uc131\ubd84\uc778 L. acidophilus, L. casei, Bifidobacterium bifidum\uc774 \ud63c\ud569\ub41c \ucea1\uc290\uc758 \uc12d\ucde8\uac00 \uc8fc\uc694 \uc6b0\uc6b8\uc7a5\uc560\ub97c \uacaa\ub294 \ud658\uc790\uc758 \uc6b0\uc6b8\uc99d\uc744 \uc644\ud654\uc2dc\ud0ac \uc218 \uc788\uc73c\uba70, L. acidophilus \ubc0f \uae30\ud0c0 7\uc885\uc758 \ud504\ub85c\ubc14\uc774\uc624\ud2f1\uc2a4\ub97c \ud3ec\ud568\ud55c \uc694\uac70\ud2b8 \uc12d\ucde8\uac00 \uc815\uc2e0\uac74\uac15\uc5d0 \ub3c4\uc6c0\uc744 \uc900\ub2e4\ub294 \uc5f0\uad6c \uacb0\uacfc\ub3c4 \uc788\uc2b5\ub2c8\ub2e4(25, 26). \ub610\ud55c \ubaa8\uccb4 \ubd84\ub9ac\ub85c \uc720\ubc1c\ub41c \uc6b0\uc6b8\uc99d \ub3d9\ubb3c \ubaa8\ub378\uc5d0\uc11c\ub294 Bifidobacterium infantis\uc758 \ud22c\uc5ec\uac00 \ud56d\uc6b0\uc6b8 \ud6a8\ub2a5\uc744 \ub098\ud0c0\ub0b4\uc5c8\uc2b5\ub2c8\ub2e4(27).

<\/p>\n\n\n\n

\uc774\ubc88 \uc5f0\uad6c\ub97c \ud1b5\ud574 \ud504\ub85c\ubc14\uc774\uc624\ud2f1\uc2a4\uac00 \ub09c\uc18c \uc808\uc81c\ub85c \uc720\ubc1c\ub41c \ub3d9\ubb3c\uc758 \uc6b0\uc6b8\uc99d \uc720\uc0ac \ud589\ub3d9\uc744 \uc644\ud654\uc2dc\ud0ac \uc218 \uc788\uc73c\uba70, \ud2b9\ud788 L. acidophilus YT1\uacfc \uac19\uc740 \ud2b9\uc815 \ubbf8\uc0dd\ubb3c\uc774 \uac31\ub144\uae30\uc758 \uc6b0\uc6b8\uc99d\uc744 \uc644\ud654\ud560 \uc218 \uc788\uc74c\uc744 \ud655\uc778\ud558\uc600\uc2b5\ub2c8\ub2e4.



<\/p>\n\n\n\n

YT1 \ud22c\uc5ec\ub97c \ud1b5\ud55c \uace8\ubc00\ub3c4 \uc99d\uac00<\/h2>\n\n\n\n

\uac31\ub144\uae30 \ubaa8\ub378 \ub3d9\ubb3c\uc758 12\uc8fc \ud6c4 \uace8\ubc00\ub3c4 \uce21\uc815 \uacb0\uacfc(Fig. 3), OVX \uadf8\ub8f9\uc5d0\uc11c\ub294 Sham \uadf8\ub8f9\uc5d0 \ube44\ud574 \uace8\ubc00\ub3c4\uac00 \uc720\uc758\uc801\uc73c\ub85c \uac10\uc18c\ud558\uc600\uc2b5\ub2c8\ub2e4(P<0.05). \uadf8\ub7ec\ub098 estradiol \ud22c\uc5ec \uadf8\ub8f9\uacfc YT1 \ud22c\uc5ec \uadf8\ub8f9\uc5d0\uc11c\ub294 OVX \uadf8\ub8f9\uc5d0 \ube44\ud574 \uace8\ubc00\ub3c4\uac00 \uc720\uc758\uc801\uc73c\ub85c \uc99d\uac00\ud558\uc600\uc2b5\ub2c8\ub2e4(P<0.05). \uc774\ub97c \ud1b5\ud574 \ub09c\uc18c \uc808\uc81c\ub85c \uc778\ud55c \uace8\ubc00\ub3c4 \uac10\uc18c\uac00 L. acidophilus YT1 \ud22c\uc5ec\ub97c \ud1b5\ud574 \uc644\ud654\ub428\uc744 \ud655\uc778\ud558\uc600\uc2b5\ub2c8\ub2e4.

<\/p>\n\n\n\n

\"\"<\/figure>\n\n\n\n


\uc5ec\uc131\uc758 \uace8\ub7c9\uc740 \ub300\ub7b5 30\ub300\uc5d0 \ucd5c\uace0\uce58\uc5d0 \ub2ec\ud558\uba70, \uc774\ud6c4\ub85c\ub294 \uace8\ud761\uc218\uc640 \uace8\ud615\uc131\uc774 \uade0\ud615\uc744 \uc720\uc9c0\ud558\uba70 \uad50\uccb4\ub418\ub294 \uc7ac\ud615\uc131 \uacfc\uc815\uc744 \ud1b5\ud574 \uc720\uc9c0\ub429\ub2c8\ub2e4. \ud2b9\ud788 \ud3d0\uacbd\uae30 \uc774\ud6c4\uc5d0\ub294 \uace8\ud615\uc131\uc774 \uace8\ud761\uc218\ubcf4\ub2e4 \uc801\uac8c \uc77c\uc5b4\ub098 \uace8\ub7c9\uc774 \uac10\uc18c\ud569\ub2c8\ub2e4(4). \uac31\ub144\uae30\uc5d0 \ubc1c\uc0dd\ud558\ub294 \uace8\uc190\uc2e4\uc740 \uc5d0\uc2a4\ud2b8\ub85c\uac90 \ub18d\ub3c4\uc640 \uc5f0\uad00\ub418\uba70, \uad6d\ub0b4 \uc5f0\uad6c\uc5d0 \ub530\ub974\uba74 \uc5d0\uc2a4\ud2b8\ub85c\uac90 \ud22c\uc5ec\ub97c \ud1b5\ud574 \uace8\ubc00\ub3c4\uac00 \uc99d\uac00\ud55c\ub2e4\uace0 \ubcf4\uace0\ub418\uc5c8\uc2b5\ub2c8\ub2e4(28, 29).

<\/p>\n\n\n\n

\uac31\ub144\uae30 \ub3d9\ubb3c \ubaa8\ub378\uc5d0\uc11c\ub3c4 \uace8\ubc00\ub3c4\uc758 \uac10\uc18c\uac00 \ubcf4\uace0\ub418\uba70, \uc774\ub7ec\ud55c \uace8\ubc00\ub3c4\uc758 \uac10\uc18c\ub294 estradiol \ud22c\uc5ec\ub97c \ud1b5\ud574 \uc720\uc758\uc801\uc73c\ub85c \uc99d\uac00\ud558\ub294 \uac83\uc73c\ub85c \uc54c\ub824\uc838 \uc788\uc2b5\ub2c8\ub2e4(30). \ud504\ub85c\ubc14\uc774\uc624\ud2f1\uc2a4\uc758 \ud22c\uc5ec\uac00 \uace8\ubc00\ub3c4\ub97c \uc99d\uac00\uc2dc\ud0a8\ub2e4\ub294 \uac83\uc740 \uc774\uc804 \uc5f0\uad6c\uc5d0\uc11c\ub3c4 \ud655\uc778\ub418\uc5c8\uc2b5\ub2c8\ub2e4. \ub09c\uc18c \uc808\uc81c\ub85c \uc778\ud574 \uace8\ubc00\ub3c4\uac00 \uac10\uc18c\ud558\ub294 \ub3d9\ubb3c \ubaa8\ub378\uc5d0\uc11c Bifidobacterium longum(31) \ubc0f L. reuteri(32)\uc758 \ud22c\uc5ec\uac00 \uace8\ubc00\ub3c4\uc758 \uc99d\uac00\uc640 \uad00\ub828\ub418\uc5b4 \uc788\uc74c\uc774 \ubcf4\uace0\ub418\uc5c8\uc2b5\ub2c8\ub2e4.



<\/p>\n\n\n\n

YT1 \ud22c\uc5ec\ub97c \ud1b5\ud55c \uccb4\uc911\uacfc \uccb4\uc9c0\ubc29 \ubcc0\ud654<\/h2>\n\n\n\n

\uac31\ub144\uae30 \uc5ec\uc131\ub4e4\uc758 \uccb4\uc911\uacfc \uccb4\uc9c0\ubc29\uc758 \uc99d\uac00\ub294 \uc6b0\uc6b8\uc99d\ubfd0\ub9cc \uc544\ub2c8\ub77c \uace8\ub2e4\uacf5\uc99d \ubc1c\ubcd1\uacfc\ub3c4 \uad00\ub828\uc774 \uc788\uc2b5\ub2c8\ub2e4(33). \uc774\ub7ec\ud55c \uc99d\uac00\ub41c \uccb4\uc911\uc740 \ud638\ub974\ubaac \ub300\uccb4 \uc694\ubc95\uc744 \ud1b5\ud574 \uc77c\uc815 \uc815\ub3c4 \uc644\ud654\ud560 \uc218 \uc788\ub2e4\ub294 \uac83\uc774 \uc54c\ub824\uc838 \uc788\uc2b5\ub2c8\ub2e4. \uac31\ub144\uae30 \ub3d9\ubb3c \ubaa8\ub378\uc5d0\uc11c\ub3c4 \uccb4\uc911\uc774 \uc99d\uac00\ud558\ub294 \uacbd\ud5a5\uc744 \ubcf4\uc774\uba70, \uc5d0\uc2a4\ud2b8\ub85c\uac90 \ud22c\uc5ec \uc2dc \uccb4\uc911\uc774 \uac10\uc18c\ud558\uba70 \uc774\ub7ec\ud55c \uc791\uc6a9\uc740 \uc5d0\uc2a4\ud2b8\ub85c\uac90 \uc54c\ud30c \uc218\uc6a9\uccb4\ub97c \ud1b5\ud574 \uc77c\uc5b4\ub0a9\ub2c8\ub2e4(34, 35). \uc2dd\ubb3c\uc131 \uc5d0\uc2a4\ud2b8\ub85c\uac90\ub3c4 \uc5d0\uc2a4\ud2b8\ub85c\uac90\uacfc \uc720\uc0ac\ud558\uac8c \uac31\ub144\uae30\uc5d0\uc11c \uc99d\uac00\ub41c \uccb4\uc911\uc744 \uac10\uc18c\uc2dc\ud0ac \uc218 \uc788\uc73c\uba70, \ud2b9\ud788 \uc774\uc18c\ud50c\ub77c\ubcf8(isoflavones)\uc758 \ud22c\uc5ec\uac00 \uccb4\uc911\uc744 \uac10\uc18c\uc2dc\ud0a8\ub2e4\ub294 \uc5f0\uad6c \uacb0\uacfc\uac00 \uc788\uc2b5\ub2c8\ub2e4(36, 37).

<\/p>\n\n\n\n

\"\"<\/figure>\n\n\n\n


\ubcf8 \uc2e4\ud5d8\uc5d0\uc11c\ub294 \ub09c\uc18c\uc808\uc81c\ub85c \uc778\ud574 \uac31\ub144\uae30 \ubaa8\ub378\uc744 \uc720\ub3c4\ud55c \ud6c4 Sham \uadf8\ub8f9\uacfc \ube44\uad50\ud558\uc5ec \uccb4\uc911\uc774 \uae09\uaca9\ud788 \uc99d\uac00\ud568\uc744 \ud655\uc778\ud558\uc600\uc2b5\ub2c8\ub2e4. \uadf8\ub7ec\ub098 estradiol \ud22c\uc5ec \uadf8\ub8f9\uc5d0\uc11c\ub294 \uc774\ub7ec\ud55c \uccb4\uc911 \uc99d\uac00\uac00 \uac10\uc18c\ud558\uc600\uc73c\uba70, \ud504\ubc14\uc774\uc624\ud2f1\uc2a4 \ucc98\ub9ac \uadf8\ub8f9\uc5d0\uc11c\ub294 \uccb4\uc911 \ubcc0\ud654\uac00 \ub098\ud0c0\ub098\uc9c0 \uc54a\uc558\uc2b5\ub2c8\ub2e4(Fig. 4A).

<\/p>\n\n\n\n

\uccb4\uc9c0\ubc29 \uce21\uc815\uc5d0\uc11c\ub294 OVX \uadf8\ub8f9(1.016\u00b10.07 g)\uc774 Sham \uadf8\ub8f9(0.3783\u00b10.16 g)\uc5d0 \ube44\ud574 \uc720\uc758\uc801\uc73c\ub85c \uccb4\uc9c0\ubc29\uc774 \uc99d\uac00\ud558\uc600\uc73c\uba70(P<0.001), estradiol \ud22c\uc5ec \uadf8\ub8f9(0.5077\u00b10.09 g)\uacfc L. acidophilus YT1 \ud22c\uc5ec \uadf8\ub8f9(0.7710\u00b10.08 g)\uc5d0\uc11c\ub294 \uc99d\uac00\ud55c \uccb4\uc9c0\ubc29\uc774 \uac10\uc18c\ud568\uc744 \ud655\uc778\ud558\uc600\uc2b5\ub2c8\ub2e4(P<0.001, P<0.05, Fig. 4B).

<\/p>\n\n\n\n

\ub610\ud55c \uc0ac\ub8cc \ubc0f \uc2dd\uc218 \uc12d\ucde8\ub7c9\uc744 \ub7ab\ud2b8\uc758 \ubb34\uac8c\ub85c \ub098\ub208 \uacb0\uacfc(Fig. 4C, 4D), OVX \uadf8\ub8f9(14.95\u00b10.2675%)\uc5d0\uc11c\ub294 Sham \uadf8\ub8f9(20.1\u00b10.7425%)\uc5d0 \ube44\ud574 \uc2dd\uc218 \uc12d\ucde8\ub7c9\/\ubb34\uac8c \uac12\uc774 \uc720\uc758\uc801\uc73c\ub85c \uac10\uc18c\ud558\uc600\uc73c\uba70(P<0.001), estradiol \ud22c\uc5ec \uadf8\ub8f9(20.28\u00b10.5741%)\uacfc YT1 \ud22c\uc5ec \uadf8\ub8f9(17.07\u00b10.5458%)\uc5d0\uc11c\ub294 OVX \uadf8\ub8f9 \ub300\ube44 \uc720\uc758\uc801\uc73c\ub85c \uc99d\uac00\ud558\uc600\uc2b5\ub2c8\ub2e4(P<0.001, P<0.01).

<\/p>\n\n\n\n

\uc774\ub7ec\ud55c \uacb0\uacfc\ub294 OVX\ub85c \uc778\ud574 \uac31\ub144\uae30 \uc720\ub3c4 \uc2dc \uc99d\uac00\ud55c \uccb4\uc911\uc5d0 \ube44\ud574 \uc0ac\ub8cc \uc12d\ucde8\ub7c9\uc774 \uac10\uc18c(38, 39)\ud558\uace0 \uc2dd\uc218 \uc12d\ucde8\ub7c9\ub3c4 \uac10\uc18c(40)\ud558\uc600\ub2e4\ub294 \ub2e4\ub978 \uc5f0\uad6c\ub4e4\uacfc \uc77c\uce58\ud569\ub2c8\ub2e4. Cengiz \ub4f1\uc740 L. acidophilus\ub97c \ud3ec\ud568\ud55c \ud504\ub85c\ubc14\uc774\uc624\ud2f1\uc2a4\ub97c \ud22c\uc5ec\ud558\uc600\uc744 \ub54c \uc0ac\ub8cc \uc12d\ucde8\ub7c9\uc774 \uc99d\uac00\ud558\uc600\uc73c\uba70 FCR(feed conversion ratio)\uc5d0\ub294 \ubcc0\ud654\uac00 \uc5c6\uc5c8\ub2e4\uace0 \ubc1d\ud614\uc2b5\ub2c8\ub2e4(41). \ubcf8 \uc5f0\uad6c\uc5d0\uc11c\ub3c4 L. acidophilus YT1 \ud22c\uc5ec \ud6c4\uc5d0 \uc0ac\ub8cc \uc12d\ucde8\ub7c9\uc774 \uc99d\uac00\ud558\uc600\uc2b5\ub2c8\ub2e4. <\/p>\n\n\n\n



\ub610\ud55c \uac31\ub144\uae30 \ub3d9\ubb3c\ubaa8\ub378\uc5d0 L. paracasei\ub97c \ud3ec\ud568\ud55c \ud504\ub85c\ubc14\uc774\uc624\ud2f1\uc2a4\ub97c \ud22c\uc5ec\ud558\uc600\uc744 \ub54c \uace8\ubc00\ub3c4\ub294 \uc99d\uac00\ud558\uc9c0\ub9cc \uccb4\uc911 \ubcc0\ud654\uac00 \uc5c6\ub2e4\ub294 \uac83\uc774 \ubcf4\uace0\ub418\uc5c8\uc2b5\ub2c8\ub2e4(42). \ucd5c\uadfc \uc131 \ud638\ub974\ubaac \ubd80\uc871\uc5d0 \ub530\ub978 \uace8\ubc00\ub3c4 \uc800\ud558\uc5d0 \uc788\uc5b4 \uc7a5\ub0b4\ubbf8\uc0dd\ubb3c\uc758 \uc5ed\ud560\uc5d0 \ub300\ud55c \uc5f0\uad6c\uac00 \ud65c\ubc1c\ud788 \uc9c4\ud589\ub418\uace0 \uc788\uc2b5\ub2c8\ub2e4.

<\/p>\n\n\n\n

\uc131 \ud638\ub974\ubaac \ubd80\uc871\uc740 \uc7a5 \ud22c\uacfc\ub3c4(gut permeability)\ub97c \uc99d\uac00\uc2dc\ud0a4\uace0 TNF-\u03b1, RANKL \ubc0f IL-17\uacfc \uac19\uc740 \ud30c\uace8\uc138\ud3ec\uc131 \uc0ac\uc774\ud1a0\uce74\uc778(osteoclastogenic cytokine) \uc0dd\uc131\uc744 \uc99d\uac00\uc2dc\ud0b5\ub2c8\ub2e4. \uadf8\ub7ec\ub098 \ubb34\uade0 \ub9c8\uc6b0\uc2a4\uc5d0\uc11c\ub294 \uc774\ub7ec\ud55c \ud30c\uace8\uc138\ud3ec\uc131 \uc0ac\uc774\ud1a0\uce74\uc778\uc774 \uc99d\uac00\ud558\uc9c0 \uc54a\uc73c\uba70, \ud504\ub85c\ubc14\uc774\uc624\ud2f1\uc2a4\uc5d0 \uc758\ud574 \uace8\uc190\uc2e4\uc744 \uc608\ubc29\ud560 \uc218 \uc788\ub2e4\ub294 \uc5f0\uad6c\uac00 \ubc1c\ud45c\ub418\uc5c8\uc2b5\ub2c8\ub2e4(43). \uc774\ub85c \ubbf8\ub8e8\uc5b4 \ubcfc \ub54c \uc7a5\ub0b4\ubbf8\uc0dd\ubb3c\uad70\uc774 \uc131 \ud638\ub974\ubaac \uacb0\ud54d\uc5d0 \uc758\ud574 \ubc1c\uc0dd\ud558\ub294 \uace8\uc190\uc2e4\uc5d0 \uc911\uc694\ud55c \uc5ed\ud560\uc744 \ud558\uace0 \uc788\uc74c\uc744 \uc54c \uc218 \uc788\uc73c\uba70, L. acidophilus YT1\uc758 \uac31\ub144\uae30 \uc99d\uc0c1 \uc644\ud654 \ud6a8\ub2a5\ub3c4 \uc774\uc640 \uad00\ub828\ub418\uc5b4 \uc788\uc744 \uac83\uc73c\ub85c \uc0dd\uac01\ub429\ub2c8\ub2e4.



<\/p>\n\n\n\n

YT1 \ucc98\ub9ac\uc5d0 \uc758\ud55c \uc7a5\ubcbd \uae30\ub2a5 \uac15\ud654<\/h2>\n\n\n\n

\uc131 \uc2a4\ud14c\ub85c\uc774\ub4dc\uc778 \uc5d0\uc2a4\ud2b8\ub85c\uac90\uc758 \uacb0\ud54d\uc740 \uc7a5\ub0b4 \ud22c\uacfc\uc131\uc744 \uc99d\uac00\uc2dc\ud0ac \uc218 \uc788\uc73c\uba70(43), \uc7a5\uad00\uc758 \ud2b9\uc815 \ubd80\uc704\ub098 \uc5d0\uc2a4\ud2b8\ub85c\uac90 \uacb0\ud54d \uc2dc\uae30\uc5d0 \ub530\ub77c \uc7a5\ub0b4 \ud22c\uacfc\uc131 \ubcc0\ud654\uc5d0 \uc601\ud5a5\uc744 \ubbf8\uce5c\ub2e4\uace0 \ubcf4\uace0\ub418\uc5c8\uc2b5\ub2c8\ub2e4(44). \uc7a5\ub0b4 \ud22c\uacfc\uc131\uc740 \uc12d\ucde8\ud55c \uc2dd\ud488\uc774\ub098 \uc758\uc57d\ud488\uc5d0 \uc758\ud574\uc11c\ub3c4 \uc601\ud5a5\uc744 \ubc1b\uc744 \uc218 \uc788\uc2b5\ub2c8\ub2e4. \uacbd\uad6c\ub85c \uc12d\ucde8\ub41c \uc720\uc0b0\uade0\uc740 \uc18c\ud654\uae30\uad00\uc744 \uac70\uccd0 \uc7a5\uc5d0\uc11c \uc77c\uc815 \uae30\uac04 \ub3d9\uc548 \uba38\ubb34\ub974\uba70, \uc774\ub294 \uc778\uccb4 \uc7a5\uad00 \uc0c1\ud53c\uc138\ud3ec\uc640\uc758 \uc9c1\uc811\uc801\uc778 \uc811\ucd09\uc744 \ud1b5\ud574 \uc7a5\ub0b4 \ud22c\uacfc\uc131 \ubcc0\ud654\uc5d0 \uc601\ud5a5\uc744 \uc904 \uc218 \uc788\uc2b5\ub2c8\ub2e4.

<\/p>\n\n\n\n

\ubcf8 \uc5f0\uad6c\uc5d0\uc11c\ub294 Caco-2 \ub2e8\uc138\ud3ec\uce35\uc744 \uc0ac\uc6a9\ud558\uc5ec L. acidophilus YT1\uc758 \uc7a5\ub0b4 \ud22c\uacfc\uc131 \uad00\ub828 \uc9c0\ud45c\uc5d0 \ubbf8\uce58\ub294 \uc601\ud5a5\uc744 \ud655\uc778\ud558\uae30 \uc704\ud574 TEER(\uc138\ud3ec \uac04\uc758 \uc804\uae30 \uc800\ud56d\uce58) \uce21\uc815\uacfc OVA \ub2e8\ubc31\uc9c8\uc758 \ud1b5\uacfc\ub7c9\uc744 \ubd84\uc11d\ud558\uc600\uc2b5\ub2c8\ub2e4. L. acidophilus YT1 \ubbf8\ucc98\ub9ac \uadf8\ub8f9(195.3\u00b16.629 \u03a9\uff65cm2)\uc5d0 \ube44\ud574 L. acidophilus YT1 \ucc98\ub9ac \uadf8\ub8f9(209\u00b17.739 \u03a9\uff65cm2)\uc5d0\uc11c TEER \uc218\uce58\uac00 \uc720\uc758\uc801\uc73c\ub85c \uc99d\uac00\ud558\uc600\uc73c\uba70(P<0.05), OVA \ub2e8\ubc31\uc9c8\uc758 \ud1b5\uacfc\ub7c9\uc774 1.945\u00b10.207 \u03bcg\/mL\uc5d0\uc11c 1.511\u00b10.0532 \u03bcg\/mL\ub85c \uc720\uc758\uc801\uc73c\ub85c \uac10\uc18c\ud55c \uac83\uc744 \ud655\uc778\ud558\uc600\uc2b5\ub2c8\ub2e4(P<0.05, Fig. 5A, 5B). \uc774\ub7ec\ud55c TEER\uc758 \uc99d\uac00\ub294 \uc7a5\uad00 \uc0c1\ud53c\uc138\ud3ec\uc758 \uc138\ud3ec \uac04 \ubc00\ucc29\uc131\uc774 L. acidophilus YT1\uc5d0 \uc758\ud574 \uc99d\uac00\ud55c \uac83\uc744 \uc758\ubbf8\ud569\ub2c8\ub2e4. \uc774\ub97c \ud1b5\ud574 \ub2e8\ubc31\uc9c8 \ud1b5\uacfc \uc5b5\uc81c\uc5d0\ub3c4 \uc601\ud5a5\uc744 \uc900 \uac83\uc73c\ub85c \ubcf4\uc785\ub2c8\ub2e4.

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\uc7a5\ubcbd\uc758 \ud22c\uacfc\uc131\uc740 \uc138\ud3ec \uac04\uc758 \ubc00\ucc29\ub3c4\uc5d0 \ub530\ub77c \uc870\uc808\ub418\uba70, \uc774\ub97c \uc704\ud574 \ub2e4\uc591\ud55c \ub2e8\ubc31\uc9c8\ub4e4\uc774 \ubcf5\ud569\uccb4\ub97c \ud615\uc131\ud558\uc5ec Tight junction\uc744 \uad6c\uc131\ud558\uace0 \uc870\uc808\ud569\ub2c8\ub2e4(46). \ubcf8 \uc5f0\uad6c\uc5d0\uc11c\ub294 L. acidophilus YT1 \ucc98\ub9ac\ub85c \uc778\ud574 Tight junction\uc758 \uc8fc\uc694 \uc720\uc804\uc790 \ubc1c\ud604\ub7c9\uc774 \uc720\uc758\uc801\uc73c\ub85c \uc99d\uac00\ud55c \uac83\uc744 \ud655\uc778\ud558\uc600\uc2b5\ub2c8\ub2e4(Fig. 5C).

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\uc704\uc758 \uc2e4\ud5d8 \uacb0\uacfc\ub97c \ud1b5\ud574 L. acidophilus YT1\uc774 Tight junction \uc720\uc804\uc790 \ubc1c\ud604 \uc0c1\ud5a5\uc870\uc808\uc744 \ud1b5\ud574 \uc7a5\ubcbd \uae30\ub2a5\uc744 \uac15\ud654\uc2dc\ud0b4\uc744 \ud655\uc778\ud560 \uc218 \uc788\uc5c8\uc2b5\ub2c8\ub2e4. \uc774\ub7ec\ud55c L. acidophilus YT1\uc758 \ud65c\uc131\uc740 \uc131 \ud638\ub974\ubaac \uacb0\ud54d\uc73c\ub85c \uc778\ud574 \uc7a5\ub0b4 \ud22c\uacfc\uc131\uc774 \uc99d\uac00\ud558\ub294 \uac83\uc744 \uc608\ubc29\ud558\uace0 \ud68c\ubcf5\ud558\ub294 \ub370\uc5d0\ub3c4 \uc801\uc6a9\ud560 \uc218 \uc788\uc744 \uac83\uc73c\ub85c \ud310\ub2e8\ub429\ub2c8\ub2e4.
<\/p>\n\n\n

\n
\"\"<\/figure><\/div>\n\n\n


\uac31\ub144\uae30(\ud3d0\uacbd)\ub294 \ub098\uc774\uac00 \ub4e4\uba74\uc11c \ub09c\uc18c\uc758 \ub178\ud654\ub85c \uc778\ud574 \uc0dd\uc2dd \ud638\ub974\ubaac\uc758 \uc0dd\uc0b0\uc774 \uac10\uc18c\ud558\ub294 \uc790\uc5f0\uc2a4\ub7ec\uc6b4 \uc2e0\uccb4\uc801 \ubcc0\ud654 \uacfc\uc815\uc774\uba70, \uc774\uc5d0 \ub530\ub77c \uc218\ubc18\ub418\ub294 \uc99d\uc0c1\uc73c\ub85c \uc778\ud574 \uc0b6\uc758 \uc9c8\uc774 \uc800\ud558\ub420 \uc218 \uc788\uc2b5\ub2c8\ub2e4. \uac31\ub144\uae30 \uc99d\uc0c1 \uc644\ud654\ub97c \uc704\ud574 \uc8fc\ub85c \ud638\ub974\ubaac \ub300\uccb4 \uc694\ubc95\uc774 \uc0ac\uc6a9\ub418\uc9c0\ub9cc, \uc7a5\uae30\uac04 \uc0ac\uc6a9 \uc2dc \ubd80\uc791\uc6a9\uc774 \ubc1c\uc0dd\ud560 \uc218 \uc788\uc5b4 \uc0c8\ub85c\uc6b4 \uce58\ub8cc\ubc95\uc774 \ud544\uc694\ud569\ub2c8\ub2e4.

<\/p>\n\n\n\n

\ud504\ub85c\ubc14\uc774\uc624\ud2f1\uc2a4\ub294 \uc7a5 \uac74\uac15, \ube44\ub9cc, \uba74\uc5ed \ub4f1\uc5d0 \uc720\uc775\ud55c \ud6a8\uacfc\ub85c \uc798 \uc54c\ub824\uc838 \uc788\uc73c\uba70, \ucd5c\uadfc \uc5f0\uad6c\uc5d0\uc11c\ub294 \uac31\ub144\uae30\uc5d0\ub3c4 \uc720\uc6a9\ud55c \ud6a8\uacfc\uac00 \uc788\ub2e4\uace0 \ubcf4\uace0\ub418\uace0 \uc788\uc2b5\ub2c8\ub2e4. \uc774\uc5d0 \ubcf8 \uc5f0\uad6c\uc5d0\uc11c\ub294 \ub09c\uc18c\uc808\uc81c \ub3d9\ubb3c\ubaa8\ub378\uc744 \uc0ac\uc6a9\ud558\uc5ec Lactobacillus acidophilus YT1\uc774 \uac31\ub144\uae30 \uc99d\uc0c1\uc5d0 \ubbf8\uce58\ub294 \ud6a8\ub2a5\uc744 \ud655\uc778\ud558\uc600\uc2b5\ub2c8\ub2e4. \uc2e4\ud5d8 \uacb0\uacfc\uc5d0 \ub530\ub974\uba74 L. acidophilus YT1 \ud22c\uc5ec \uadf8\ub8f9\uc5d0\uc11c\ub294 \ud1b5\uc99d \ubbfc\uac10\ub3c4, \uc6b0\uc6b8\uc99d \uad00\ub828 \ud589\ub3d9, \uccb4\uc9c0\ubc29\ub7c9\uc758 \uc99d\uac00, \uace8\ubc00\ub3c4\uc758 \uac10\uc18c\uc640 \uac19\uc740 \uac31\ub144\uae30 \uc99d\uc0c1\uc774 \uc720\uc758\ud558\uac8c \uac1c\uc120\ub418\uc5c8\uc2b5\ub2c8\ub2e4.

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\ub610\ud55c, L. acidophilus YT1\uc740 \uc7a5 \uc0c1\ud53c\uc138\ud3ec\uc758 \uc7a5\ubcbd \uac15\ud654\ub97c \ud1b5\ud574 \uc7a5\ub0b4 \ud22c\uacfc\uc131\uc744 \uac15\ud654\uc2dc\ud0ac \uc218 \uc788\uc5c8\uc2b5\ub2c8\ub2e4. \uc774\ub97c \ud1b5\ud574 L. acidophilus YT1\uc740 \uac31\ub144\uae30 \uc5ec\uc131\uc758 \uac74\uac15\uc744 \uc704\ud55c \ud6a8\uacfc\uc801\uc778 \uc635\uc158\uc73c\ub85c \uace0\ub824\ub420 \uc218 \uc788\uc2b5\ub2c8\ub2e4. \ucd94\uac00\uc801\uc778 \uc5f0\uad6c\ub97c \ud1b5\ud574 \uac31\ub144\uae30 \uc5ec\uc131\uc744 \uc704\ud55c \uac74\uac15 \uae30\ub2a5\uc131 \uc2dd\ud488\uc758 \uac1c\ubc1c\uc774 \uac00\ub2a5\ud560 \uac83\uc73c\ub85c \uae30\ub300\ub429\ub2c8\ub2e4.
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\uc774\uc0c1 \uac31\ub144\uae30 \uc720\uc0b0\uade0 YT1, \uc2e4\ud5d8 \uadfc\uac70 \uc815\ub9ac\ud558\uc5ec \uc548\ub0b4\ud574 \ub4dc\ub838\uc2b5\ub2c8\ub2e4.<\/strong>
\uc544\ub798\uc758 \ub9c1\ud06c\ub294 \uac31\ub144\uae30 \uc99d\uc0c1 \uc644\ud654\uc5d0 \uad00\ud55c \uc815\ubcf4\ub85c \ud568\uaed8 \ud655\uc778 \ud558\uba74 \ub3c4\uc6c0\uc744 \uc8fc\ub294 “\uac31\ub144\uae30 \uc99d\uc0c1 \uc644\ud654, \uac74\uac15\ud55c \uc7a5\ub0b4 \uc138\uade0\ucd1d\uc758 \uc5ed\ud560”<\/a>\uc744 \ud655\uc778\ud558\uc2e4 \uc218 \uc788\uc2b5\ub2c8\ub2e4.<\/p>\n\n\n\n

\nhttps:\/\/health2816.mycafe24.com\/%ea%b0%b1%eb%85%84%ea%b8%b0-%ec%a6%9d%ec%83%81-%ec%99%84%ed%99%94-%ea%b1%b4%ea%b0%95%ed%95%9c-%ec%9e%a5%eb%82%b4-%ec%84%b8%ea%b7%a0%ec%b4%9d%ec%9d%98-%ec%97%ad%ed%95%a0\/\n<\/div><\/figure>\n\n\n\n



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REFERENCES<\/h2>\n\n\n\n
    \n
  1. Monteleone P, Mascagni G, Giannini A, Genazzani AR, Simoncini T. 2018. Symptoms of menopause\uff0dglobal prevalence, physiology and implications. Nat Rev Endocrinol 14: 199-215.<\/li>\n\n\n\n
  2. Nikolov V, Petkova M. 2010. Pain sensitivity among women with low estrogen levels. Procedia Soc Behav Sci 5: 289-293.<\/li>\n\n\n\n
  3. Perez-Lopez FR, Perez-Roncero G, Fernandez-Inarrea J, Fernandez-Alonso AM, Chedraui P, Llaneza P. 2014. Resilience, depressed mood, and menopausal symptoms in postmenopausal women. Menopause 21: 159-164.<\/li>\n\n\n\n
  4. Sasson H, Carpenter CL. 2013. Achievement of peak bone mass in women is critically dependent on adolescent calcium intake. OA Sports Medicine 1: 16.<\/li>\n\n\n\n
  5. Davison S, Davis SR. 2003. Hormone replacement therapy: current controversies. Clin Endocrinol 58: 249-261.<\/li>\n\n\n\n
  6. Tavani A, La Vecchia C. 1999. The adverse effects of hormone replacement therapy. Drugs Aging 14: 347-357.<\/li>\n\n\n\n
  7. Rossouw JE, Anderson GL, Prentice RL, LaCroix AZ, Kooperberg C, Stefanick ML, Jackson RD, Beresford SA, Howard BV, Johnson KC, Kotchen JM, Ockene J. 2002. Risks and benefits of estrogen plus progestin in healthy postmenopausal women: principal results from the Women\u2019s Health Initiative randomized controlled trial. JAMA 288: 321-333.<\/li>\n\n\n\n
  8. Kang SJ, Choi BR, Kim SH, Yi HY, Park HR, Song CH, Ku SK, Lee YJ. 2017. Anti-climacterium effects of pomegranate concentrated solutions in ovariectomized ddY mice. Exp Ther Med 13: 1249-1266.<\/li>\n\n\n\n
  9. Wang L, Guo MJ, Gao Q, Yang JF, Yang L, Pang XL, Jiang XJ. 2018. The effects of probiotics on total cholesterol: A meta-analysis of randomized controlled trials. Medicine 97: e9679.<\/li>\n\n\n\n
  10. Al-Ghazzewi FH, Tester RF. 2014. Impact of prebiotics and probiotics on skin health. Benefic Microbes 5: 99-107.<\/li>\n\n\n\n
  11. Stevens GA. 2016. Probiotics for digestive health: A review of information resources. J Consum Health Internet 20: 167- 172.<\/li>\n\n\n\n
  12. Kober MM, Bowe WP. 2015. The effect of probiotics on immune regulation, acne, and photoaging. Int J Womens Dermatol 1: 85-89.<\/li>\n\n\n\n
  13. Torii S, Torii A, Itoh K, Urisu A, Terada A, Fujisawa T, Yamada K, Suzuki H, Ishida Y, Nakamura F, Kanzato H, Sawada D, Nonaka A, Hatanaka M, Fujiwara S. 2011. Effects of oral administration of Lactobacillus acidophilus L-92 on the symptoms and serum markers of atopic dermatitis in children. Int Arch Allergy Immunol 154: 236-245.<\/li>\n\n\n\n
  14. Bull M, Plummer S, Marchesi J, Mahenthiralingam E. 2013. The life history of Lactobacillus acidophilus as a probiotic: a tale of revisionary taxonomy, misidentification and commercial success. FEMS Microbiol Lett 349: 77-87.<\/li>\n\n\n\n
  15. Dar HY, Shukla P, Mishra PK, Anupam R, Mondal RK, Tomar GB, Sharma V, Srivastava RK. 2018. Lactobacillus acidophilus inhibits bone loss and increases bone heterogeneity in osteoporotic mice via modulating Treg-Th17 cell balance. Bone Rep 8: 46-56.<\/li>\n\n\n\n
  16. Montazeri-Najafabady N, Ghasemi Y, Dabbaghmanesh MH, Talezadeh P, Koohpeyma F, Gholami A. 2018. Supportive role of probiotic strains in protecting rats from ovariectomyinduced cortical bone loss. Probiotics Antimicrob Proteins 1-10.<\/li>\n\n\n\n
  17. Heiss C, Govindarajan P, Schlewitz G, Hemdan NYA, Schliefke N, Alt V, Thormann U, Lips KS, Wenisch S, Langheinrich AC, Zahner D, Schnettler R. 2012. Induction of osteoporosis with its influence on osteoporotic determinants and their interrelationships in rats by DEXA. Med Sci Monit 18: BR199-207.<\/li>\n\n\n\n
  18. Chaplan SR, Bach FW, Pogrel JW, Chung JM, Yaksh TL. Quantitative assessment of tactile allodynia in the rat paw. J Neurosci Methods 53: 55-63.<\/li>\n\n\n\n
  19. Li LH, Wang ZC, Yu J, Zhang YQ. 2014. Ovariectomy results in variable changes in nociception, mood and depression in adult female rats. PLoS One 9: e94312.<\/li>\n\n\n\n
  20. Sanoja R, Cervero F. 2008. Estrogen modulation of ovariectomy-induced hyperalgesia in adult mice. Eur J Pain 12: 573-581.<\/li>\n\n\n\n
  21. Dardmeh F, Nielsen HI, Alipour H, Kj\u00e6rgaard B, Brandsborg E, Gazerani P. 2016. Potential nociceptive regulatory effect of probiotic Lactobacillus rhamnosus PB01 (DSM 14870) on mechanical sensitivity in diet-induced obesity model. Pain Res Manag 2016: 5080438.<\/li>\n\n\n\n
  22. Castelli V, Palumbo P, d\u2019Angelo M, Moorthy NK, Antonosante A, Catanesi M, Lombardi F, Iannotta D, Cinque B, Benedetti E, Ippoliti R, Cifone MG, Cimini A. 2018. Probiotic DSF counteracts chemotherapy induced neuropathic pain. Oncotarget 9: 27998-28008.<\/li>\n\n\n\n
  23. Wang Y, Xu Y, Sheng H, Ni X, Lu J. 2016. Exercise amelioration of depression-like behavior in OVX mice is associated with suppression of NLRP3 inflammasome activation in hippocampus. Behav Brain Res 307: 18-24.<\/li>\n\n\n\n
  24. Sasayama D, Sugiyama N, Yonekubo S, Pawlak A, Murasawa H, Nakamura M, Hayashi M, Ogawa T, Moro M, Washizuka S, Amano N, Hongo K, Ohnota H. 2017. Novel oestrogen receptor \u03b2-selective ligand reduces obesity and depressive-like behaviour in ovariectomized mice. Sci Rep 7: 4663.<\/li>\n\n\n\n
  25. Akkasheh G, Kashani-Poor Z, Tajabadi-Ebrahimi M, Jafari P, Akbari H, Taghizadeh M, Memarzadeh MR, Asemi Z, Esmaillzadeh A. 2016. Clinical and metabolic response to probiotic administration in patients with major depressive disorder: A randomized, double-blind, placebo-controlled trial. Nutrition 32: 315-320.<\/li>\n\n\n\n
  26. Mohammadi AA, Jazayeri S, Khosravi-Darani K, Solati Z, Mohammadpour N, Asemi Z, Adab Z, Djalali M, TehraniDoost M, Hosseini M, Eghtesadi S. 2016. The effects of probiotics on mental health and hypothalamic-pituitary-adrenal axis: A randomized, double-blind, placebo-controlled trial in petrochemical workers. Nutr Neurosci 19: 387-395.<\/li>\n\n\n\n
  27. Desbonnet L, Garrett L, Clarke G, Kiely B, Cryan JF, Dinan TG. 2010. Effects of the probiotic Bifidobacterium infantis in the maternal separation model of depression. Neuroscience 170: 1179-1188. Hedlund LR, Gallagher JC. 1989. The effect of age and menopause on bone mineral density of the proximal femur. J Bone Miner Res 4: 639-642.<\/li>\n\n\n\n
  28. Kim HJ, Oh YK, Lee JS, Lee DY, Choi DS, Yoon BK. 2014. Effect of transdermal estrogen therapy on bone mineral density in postmenopausal Korean women. J Menopausal Med 20: 111-117.<\/li>\n\n\n\n
  29. Lim DW, Kim YT. 2014. Anti-osteoporotic effects of Angelica sinensis (Oliv.) Diels extract on ovariectomized rats and its oral toxicity in rats. Nutrients 6: 4362-4372.<\/li>\n\n\n\n
  30. Parvaneh K, Ebrahimi M, Sabran MR, Karimi G, Hwei ANM, Abdul-Majeed S, Ahmad Z, Ibrahim Z, Jamaluddin R. 2015. Probiotics (Bifidobacterium longum) increase bone mass density and upregulate Sparc and Bmp-2 genes in rats with bone loss resulting from ovariectomy. Biomed Res Int 2015: 897639.<\/li>\n\n\n\n
  31. Britton RA, Irwin R, Quach D, Schaefer L, Zhang J, Lee T, Parameswaran N, McCabe LR. 2014. Probiotic L. reuteri treatment prevents bone loss in a menopausal ovariectomized mouse model. J Cell Physiol 229: 1822-1830.<\/li>\n\n\n\n
  32. Davis SR, Castelo-Branco C, Chedraui P, Lumsden MA, Nappi RE, Shah D, Villaseca P. 2012. Understanding weight gain at menopause. Climacteric 15: 419-429.<\/li>\n\n\n\n
  33. Chmouliovsky L, Habicht F, James RW, Lehmann T, Campana A, Golay A. 1999. Beneficial effect of hormone replacement therapy on weight loss in obese menopausal women. Maturitas 32: 147-153.<\/li>\n\n\n\n
  34. Bhardwaj P, Du B, Zhou XK, Sue E, Giri D, Harbus MD, Falcone DJ, Hudis CA, Subbaramaiah K, Dannenberg AJ.<\/li>\n\n\n\n
  35. Estrogen protects against obesity induced mammary gland inflammation in mice. Cancer Prev Res (Phila) 8: 751- 759.<\/li>\n\n\n\n
  36. Chen YM, Ho SC, Lam SSH, Ho SSS, Woo JLF. 2004. Beneficial effect of soy isoflavones on bone mineral content was modified by years since menopause, body weight, and calcium intake: a double-blind, randomized, controlled trial. Menopause 11: 246-254.<\/li>\n\n\n\n
  37. Zhang YB, Chen WH, Guo JJ, Fu ZH, Yi C, Zhang M, Na XL. 2013. Soy isoflavone supplementation could reduce body weight and improve glucose metabolism in non-Asian postmenopausal women\uff0dA meta-analysis. Nutrition 29: 8- 14.<\/li>\n\n\n\n
  38. Sanchez-Mateos S, Alonso-Gonzalez C, Gonzalez A, Martinez-Campa CM, Mediavilla MD, Cos S, Sanchez-Barcelo EJ. 2007. Melatonin and estradiol effects on food intake, body weight, and leptin in ovariectomized rats. Maturitas 58: 91-101.<\/li>\n\n\n\n
  39. Rogers NH1, Perfield JW 2nd, Strissel KJ, Obin MS, Greenberg AS. 2009. Reduced energy expenditure and increased inflammation are early events in the development of ovariectomy-induced obesity. Endocrinology 150: 2161-2168.<\/li>\n\n\n\n
  40. Pettipher ER, Hibbs TA, Smith MA, Griffiths RJ. 1997. Analgesic activity of 2-amino-4-methylpyridine, a novel NO
    synthase inhibitor. Inflamm Res 46: S135-136.<\/li>\n\n\n\n
  41. Cengiz O, Koksal BH, Tatli O, Sevim O, Ahsan U, Uner AG, Ulutas PA, Beyaz D, Buyukyoruk S, Yakan A, Onol AG. 2015. Effect of dietary probiotic and high stocking density on the performance, carcass yield, gut microflora, and stress indicators of broilers. Poult Sci 94: 2395-2403.<\/li>\n\n\n\n
  42. Ohlsson C, Engdahl C, F\u00e5k F, Andersson A, Windahl SH, Farman HH, Mov\u00e9rare-Skrtic S, Islander U, Sj\u00f6gren K. 2014. Probiotics protect mice from ovariectomy-induced cortical bone loss. PLoS One 9: e92368.<\/li>\n\n\n\n
  43. Li JY, Chassaing B, Tyagi AM, Vaccaro C, Luo T, Adams J, Darby TM, Weitzmann MN, Mulle JG, Gewirtz AT, Jones RM, Pacifici R. 2016. Sex steroid deficiency-associated bone loss is microbiota dependent and prevented by probiotics. J Clin Invest 126: 2049-2063.<\/li>\n\n\n\n
  44. Braniste V, Leveque M, Buisson-Brenac C, Bueno L, Fioramonti J, Houdeau E. 2009. Oestradiol decreases colonic permeability through oestrogen receptor \u03b2-mediated up-regulation of occludin and junctional adhesion molecule-A in epithelial cells. J Physiol 587: 3317-3328.<\/li>\n\n\n\n
  45. Ward PD, Tippin TK, Thakker DR. 2000. Enhancing paracellular permeability by modulating epithelial tight junctions. Pharm Sci Technolo Today 3: 346-358.<\/li>\n\n\n\n
  46. Forster C. 2008. Tight junctions and the modulation of barrier function in disease. Histochem Cell Biol 130: 55-70.<\/li>\n<\/ol>\n\n\n\n

    <\/p>\n\n\n\n





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